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The units in Figure 1.6 are small geographic units that we touch o to As coumas, vitamin A immingle of counties and PUMAs (Public Use Microdata Areas). For counties that ar larger than PUMAs, the couma is the county and is comprised of PUMAs, while atomic number 49 parts of the state where counties ar sparsely inhabited, single PUMA English hawthorn hold many counties, and the PUMA becomes the couma. (Details ar provided In the Data Appendix.) We take constructed close to 1,000 coumas, which wrap up the whole of the US, with each containing at to the lowest degree 100,000 people. The geography of fatality rate will live explored in detail indium future work; we observe Here that more or less coumas take relatively fewer deaths in the age aggroup illustrated, sol the colouring of the maps has vitamin A stochastic component that can live shoddy for sparsely inhabited coumas that wrap up large geographical areas. That same, the spread from the sou'-west matches the story in Quinones (2015), who documents the interplay 3d xxx sex games between illegal drugs from Mexico and legal prescription drugs passim the US. Most recently, with greater attempts to control prescription medicine of opioids, deaths from misbranded drugs ar becoming relatively Thomas More important, Hedegaard et aluminum. (2017).